Using Copy to Segment B2B Audiences for Targeted GTM Campaigns

If your idea of B2B audience segmentation is a spreadsheet with 20 tabs and a prayer, you’re not alone. Most teams still blast out the same tired messaging and hope it sticks. But if you’re running go-to-market (GTM) campaigns and need to actually move the needle, you can’t afford to treat all your leads the same. This guide is for marketers and GTM teams who want to use Copy to cut through the noise, segment B2B audiences with real intent, and send messages people actually care about.

Let’s get to it—no buzzwords, no nonsense.


Why Segmentation Actually Matters (and What to Ignore)

Before you hit “send” on another campaign, let’s be honest: most segmentation efforts are either too shallow (“C-level vs not!”) or way too complicated (17 buyer personas, anyone?). Here’s what actually matters:

  • Segmentation should make your message more relevant. If your emails or ads sound like they could go to anyone, you’re doing it wrong.
  • You don’t need infinite segments. More segments ≠ better results. Focus on the few slices that matter for your product and campaign.
  • Ignore the hype around “hyper-personalization.” Unless you’ve got an army of writers and endless data, stick to what you can actually execute.

Step 1: Define Segments That Actually Mean Something

Forget “small business” vs “enterprise” unless your campaign truly changes for each. Good segmentation is about actionable differences.

How to spot useful segments: - They reflect different pains, jobs-to-be-done, or buying triggers. - Your messaging or offer actually changes for each segment. - You have enough data to identify them.

Common B2B segments that work: - Industry: If your product solves different problems for, say, SaaS vs manufacturing, split ‘em. - Role/function: CTOs care about different things than Marketing Directors. - Seniority: Decision-makers vs end users—don’t treat them the same. - Tech stack: Selling an integration? Segment by who uses the relevant tool. - Intent signals: Did they download a whitepaper, request a demo, or just lurk? Treat them differently.

Pro tip: Run a quick “Would I say something different to this group?” test. If not, combine the segments.

Step 2: Gather the Right Data (Without Going Down a Rabbit Hole)

You can’t segment on vibes. Here’s what you actually need:

Internal data sources: - CRM and MAP fields (industry, role, company size, etc.) - Website behavior (pages viewed, resources downloaded) - Past engagement (opened emails, replied, attended webinars)

External data sources: - Enrichment tools (Clearbit, ZoomInfo, Apollo, etc.) - LinkedIn for role/function or company insights - Tech stack checkers (BuiltWith, SimilarTech)

What to skip:
Don’t waste time on vanity data you can’t use. If you can’t trust its accuracy or you’re not going to act on it, leave it out.

Step 3: Set Up Segmentation in Copy

Here’s where Copy comes in. It’s built to make segmentation and targeted messaging way less painful than your average MAP.

How to segment with Copy:

  1. Import or sync your data.
    Bring in your CRM lists, upload CSVs, or connect integrations. Clean data matters more than fancy filters.
  2. Build your segments.
    Use Copy’s filtering tools—stack filters like industry, role, company size, or intent signals.
  3. Example: “Marketing Directors in SaaS companies with >100 employees who viewed our pricing page in the last 30 days.”
  4. Save and name your segments clearly.
    Don’t call it “List 1.” Use names like “SaaS Marketers – High Intent” so your team knows what’s what.
  5. Preview and sanity-check.
    Scan through the list. If you see oddballs (e.g., students in your “CFOs” list), tweak your filters.

Pro tip: Start with broad segments, then refine. Over-segmentation leads to tiny lists and wasted time.

Step 4: Tailor Your Messaging (But Don’t Overthink It)

You’ve got your segments—now what? The magic happens when your message actually speaks to each group.

What works: - Tweak the opening line. Reference their industry, job function, or a recent action (“Saw you checked out our API docs”). - Highlight the right value prop. CTOs want reliability; marketers want leads. - Use relevant proof. Case studies from their industry or role work better than generic logos.

What to skip: - Don’t rewrite your whole campaign for every segment. Change 10–20% of the copy—the parts that matter. - Avoid cringe “personalization” (“Hi {FirstName}, hope Q3 is going well!”). Be real.

Example tweaks:

| Segment | Generic Line | Tailored Line | |---------------------|---------------------------------------------|-------------------------------------------------------| | SaaS CTOs | “Our platform scales with you.” | “Other SaaS CTOs use us to automate user onboarding.” | | Manufacturing Ops | “Save time with automation.” | “Cut downtime on your shop floor with automation.” |

Step 5: Launch, Measure, and Iterate

Don’t fall in love with your segments or messaging. Your best guess is still a guess.

How to keep it simple: - A/B test segments and messages. See what actually moves the needle—opens, replies, conversions. - Watch for segment decay. People change jobs, companies evolve. Review segments every quarter. - Kill what doesn’t work. Segments that don’t perform? Merge them or drop them.

Metrics that matter: - Engagement: Opens, clicks, replies (not just vanity metrics) - Conversion: Demos booked, trials started, pipeline created - Feedback: Actual replies—what do people say back?

Pro tip: Document what you tried and what happened. It’ll save you (and your future teammates) a ton of guesswork.

What Works (and What’s a Waste of Time)

Useful: - Segmenting based on real pains or triggers - Keeping segments manageable (think 3–5, not 20) - Iterating fast based on results

Not worth it: - Over-engineering segments with tiny differences - Personalizing every word - Chasing “AI-powered” segmentation that promises magic but delivers little

Keep It Simple, Iterate, Repeat

You don’t need a 50-slide persona deck or an AI that reads your customers’ minds. The best segmentation is the kind you’ll actually use—one that helps you say the right thing to the right people, without burning your team out. Start small, use the tools you have (like Copy), and don’t be afraid to combine or kill segments as you go.

Segmentation isn’t a one-and-done deal. It’s a process—so keep it simple, keep it honest, and keep iterating. That’s how you turn messaging from noise into action.